ACS GCI Pharmaceutical Roundtable

Author Archive

2022

Green Chemistry Articles of Interest to the Pharmaceutical Industry
Bryan, M.C.; Dalton, C.; Díaz-Rodríguez, A.; Doerfler, J.; Engl, O.D.; Ferguson, P.; Gimenez Molina, A.; Han. Z. S.; Hasford, J.; Howell, G.P., et. al. Org. Process Res. Dev. 2022, 26(2), 251-262.
https://doi.org/10.1021/acs.oprd.2c00020

Importance of Green Chemistry and Sustainable Chemistry in the Chemical Laboratory
Colberg, J.; Hii, K. K.; Koenig, S. ACS Sustain. Chem. Eng. 2022, 10(26), 8239-8241.
https://doi.org/10.1021/acssuschemeng.2c03306

Green Chemistry Articles of Interest to the Pharmaceutical Industry
Bryan, M.C.; Dalton, C.; Doerfler, J.; Engl, O.D.; Ferguson, P.; Gimenez Molina, A.; Harawa, V.; Hasford, J.; Howell, G.P., Kelly, C.B.; et. al. Org. Process Res. Dev. 2022, 26(9), 2550-2559.
https://doi.org/10.1021/acs.oprd.2c00274

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2022

Yang Hai, University of California Santa Barbara, $50,000
“Application of a PLP-dependent Mannich cyclase for biocatalytic synthesis of heterocyclic quaternary α-amino acids”

C. Oliver Kappe, University of Graz, Austria, $50,000
“Simplified PAT Strategies for Calibration-Free Real-Time Data Gathering and Utilization in Automated Flow Chemistry Platforms”

Christopher Sandford, Dartmouth College, $50,000
“Bifunctional Organocatalysts for Sustainable Peptide Bond Formation”

Nicholas Snow, Seton Hall University, $50,000
“‘Greening’ Pharmaceutical Analysis Using Gas Chromatography”

Jack Norton and Aaron Moment, Columbia University, $50,000
“Selective reduction of aromatic rings in advanced scaffolds in flow reactors with non-noble metal catalysis under mild conditions”

Masad J. Damha, McGill University, $50,000
“Oligonucleotide synthesis by resonant acoustic mixing (RAM)”

Jesús Fernández Lucas, Universidad Europea de Madrid, Spain, $25,000
“Enzymatic synthesis of C-nucleosides”

Yu Zhao, National University of Singapore, $25,000
“Electrocatalytic Functionalization of Commodity Alcohols to Produce Valuable Amines and Amides”

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2021

Duncan Browne, University College of London, $50,000
“Learning to Extrude Chemical Reactions”

Malgorzata Chwatko, University of Kentucky, $50,000
“Improvement of Peptide Yield and Solvent Reuse via Membrane Enhanced Peptides Synthesis”

Hans Renata, Scripps Research, $50,000
“Biocatalytic Synthesis of Challenging Noncanonical Amino Acids”

Jennifer Schomaker, University of Wisconsin-Madison, $50,000
“Tunable Catalytic C(sp3)-H Functionalization of Heterocyclic Scaffolds”

Qiu Wang, Duke University, $25,000
“Copper-Catalyzed Carbon-Carbon Coupling of Alcohols and Alkenes”

Han Sen Soo, Nanyang Technological University, Singapore, $25,000
“Photocatalytic Carbon-Carbon Bond Activation and Functionalization to Access Unnatural α-Amino Acids”

Mélanie Hall, University of Graz, Austria, $25,000
“Enzymatic nitration strategies for the biocatalytic synthesis of nitrogen containing molecules”

Florian Hollfelder, University of Cambridge, $25,000
“Exploring fitness landscapes of enzymes for chiral synthesis”

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2021

Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Andrews, B. I.;* Firoz, D. A.; Brueggemeier, S. B.; Diorazio L. J; Koenig, S. G.; Kopach, M.; Lee, H.; Olbrich, M. and Watson, A. J. Org. Chem. 2021, 86, 1, 49–61.
https://doi.org/10.1021/acs.joc.0c02291

Green Chemistry Articles of Interest to the Pharmaceutical Industry
Dalton, C.; Diorazio, L. J.; Doerfler, J.; Engl, O. L.; Han, Z. S.; Howell, G. P.; Latham, J.; Li, W.; McLaws, M.; Munday, R. H.; Navarro, A.; Parmentier M.; Pawlas, J.; Richardson, P.; Roiban, G-D.; Steven, A.*; Terrett, J. A.; Treitler, D.S.; and Zeng, M. Org. Process Res. Dev. 2021, 25, 4, 703–712.
https://doi.org/10.1021/acs.oprd.1c0006

Manufacturing Mass Intensity: 15 Years of Process Mass Intensity and Development of the Metric into Plant Cleaning and Beyond
Benison, C.*; Payne, P. Curr. Res. Chem. Green Sustain. Chem.
https://doi.org/10.1016/j.crgsc.2021.100229

Green Chemistry Articles of Interest to the Pharmaceutical Industry
Bryan M. C.*, Dalton, C.; Diorazio, L. J.; Doerfler, J.; Doyle, L. M.; Engl, O. D.; Gimenez Molina, A.; Han, Z. S.; Hosford, J.; Howell, G. P.; Hutchby, M.; Latham, J.; Li, W.; Munday, R. H.; Navarro, A.; Parmentier, M.; Pawlas, J.; Richardson, P. F.; Steven, A.;* Terrett, J. A. and Zeng, M. Org. Process Res. Dev. 2021, 25, 10, 2167–2176.
https://doi.org/10.1021/acs.oprd.1c00352

Making Sustainability Assessment Accessible: Tools Developed by the ACS Green Chemistry Institute Pharmaceutical Roundtable
Diorazio, L. J.; Richardson, R. F.; Sneddon, H.; Moores, A.; Briddell, C. and Martinez, I.* ACS Sustainable Chem. Eng. 2021, 9, 50, 16862–16864.
https://doi.org/10.1021/acssuschemeng.1c07651

Improved iGAL 2.0 Metric Empowers Pharmaceutical Scientists to Make Meaningful Contributions to United Nations Sustainable Development Goal 12
Roschangar, F.*; Li, J.; Zhou, Y.; Aelterman, W.; Borovika, A.; Colberg, J.; Dickson, D.; Gallou, F.; Hayler, J.D.; Koenig, S.G.; Kopach, M.E.; Kosjek, B.; Leahy, D.; O’Brien, E.; Smith, A.G.; Henry, M.; Cook, J. and Sheldon, R. A. ACS Sustainable Chem. Eng. 2021, ASAP. https://pubs.acs.org/doi/10.1021/acssuschemeng.1c01940

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