Grants

Walter Cabri, Alessandra Tolomelli, and Lucia Ferrazzano, University of Bologna, $80,000
“New technology for continuous flow liquid-phase sustainable synthesis of therapeutic peptides”

Hans Renata of Rice University, $80,000
“Biocatalytic Synthesis of Phosphorothioate-Containing Nucleosides”

Marcel Schreier and Shannon Stahl of the University of Wisconsin Madison, $80,000
“Realizing the advantages of alternating polarity electrosynthesis at constant potential through controlled mass transport”

Andrew Teixeira and Patricia Musacchio of Worcester Polytechnic Institute, $80,000
“Overcoming light penetration challenges in photochemical reactions through a micro-LED packed bed reactor”

Jeffrey Lipshultz, Stony Brook University, $40,000
“Aminomutase-Inspired Green Radical Amination”

Marvin Parasram, New York University, $40,000
“Dihydroxylation of Propellanes via Tandem Cycloaddition/Hydrogenation of Photoexcited Nitroarenes”

Bruce Arndtsen, McGill University, $40,000
“A Versatile Approach to Carboxylic Acid Derivatives with Earth Abundant Catalysts and Visible Light”

Neil Dixon, Manchester Institute of Biotechnology, $40,000
“Sustainable Solvent Production”

Yang Hai, University of California Santa Barbara, $50,000
“Application of a PLP-dependent Mannich cyclase for biocatalytic synthesis of heterocyclic quaternary α-amino acids”

C. Oliver Kappe, University of Graz, Austria, $50,000
“Simplified PAT Strategies for Calibration-Free Real-Time Data Gathering and Utilization in Automated Flow Chemistry Platforms”

Christopher Sandford, Dartmouth College, $50,000
“Bifunctional Organocatalysts for Sustainable Peptide Bond Formation”

Nicholas Snow, Seton Hall University, $50,000
“‘Greening’ Pharmaceutical Analysis Using Gas Chromatography”

Jack Norton and Aaron Moment, Columbia University, $50,000
“Selective reduction of aromatic rings in advanced scaffolds in flow reactors with non-noble metal catalysis under mild conditions”

Masad J. Damha, McGill University, $50,000
“Oligonucleotide synthesis by resonant acoustic mixing (RAM)”

Jesús Fernández Lucas, Universidad Europea de Madrid, Spain, $25,000
“Enzymatic synthesis of C-nucleosides”

Yu Zhao, National University of Singapore, $25,000
“Electrocatalytic Functionalization of Commodity Alcohols to Produce Valuable Amines and Amides”

Duncan Browne, University College of London, $50,000
“Learning to Extrude Chemical Reactions”

Malgorzata Chwatko, University of Kentucky, $50,000
“Improvement of Peptide Yield and Solvent Reuse via Membrane Enhanced Peptides Synthesis”

Hans Renata, Scripps Research, $50,000
“Biocatalytic Synthesis of Challenging Noncanonical Amino Acids”

Jennifer Schomaker, University of Wisconsin-Madison, $50,000
“Tunable Catalytic C(sp3)-H Functionalization of Heterocyclic Scaffolds”

Qiu Wang, Duke University, $25,000
“Copper-Catalyzed Carbon-Carbon Coupling of Alcohols and Alkenes”

Han Sen Soo, Nanyang Technological University, Singapore, $25,000
“Photocatalytic Carbon-Carbon Bond Activation and Functionalization to Access Unnatural α-Amino Acids”

Mélanie Hall, University of Graz, Austria, $25,000
“Enzymatic nitration strategies for the biocatalytic synthesis of nitrogen containing molecules”

Florian Hollfelder, University of Cambridge, $25,000
“Exploring fitness landscapes of enzymes for chiral synthesis”

Tristan Lambert & Phillip Milner, Cornell University, $50,000
“Bioinspired Metal-Organic Frameworks as Heterogeneous Catalysts for Peptide Synthesis”

Kamalesh K. Sirkar, New Jersey Institute of Technology, $50,000
“Develop membranes for pressure-driven separation of solutes and solvents in the 50-600 Da range from API synthesis mixtures”

Pasi Virta, University of Turku, $50,000
“Improved synthesis of nucleotide blockmers using a precipitative soluble”

Daniel J. Weix, University of Wisconsin-Madison, $50,000
“Metal-Mediated Electrochemistry: A new frontier for surfactants”

Martin Andersson, Technical University of Denmark (DTU), $25,000
“Developing New Surfactants for Easy Separation”

Soumitra Athavale & Frances H. Arnold, California Institute of Technology, $25,000
“Biocatalytic C-H bond Functionalization for the Synthesis of Enantioenriched Amines and Amides”

Matthew A. Hostetler, Marshall University, $25,000
“Cups: An Atom efficient and low-waste producing method of inverse solid-phase peptide synthesis”

Tehshik P. Yoon, University of Wisconsin-Madison, $25,000
“Oxidative C–N Cross-Coupling Enabled by Iron Photochemistry”

Ryan Shenvi, Scripps Research, $50,000
“C–N Attached-Ring Synthesis by Markovnikov Hydroamination”

Susan Olesik, The Ohio State University, $46,996
“A Study of the Environmental Impact of Analytical and Preparative Scale Supercritical Fluid Chromatographic Processes”

Fernando Albericio and Beatriz G. de la Torre, University of KwaZulu-Natal, $25,000
“Baroc, a Green α-Amino Protecting Group for Solid-Phase Peptide Synthesis”

Mark Mason, The University of Toledo, $25,000
“Iron-Catalyzed Cross-Coupling of Heterocycles”

Aaron Vannucci, University of South Carolina, $25,000
“A New Approach to Catalyst Immobilization Research: Designing Molecular Catalysts for Heterogeneous Catalysis”

Arnaud Voituriez, Institut de Chimie des Substances Naturelles, $25,000
“Towards an Electro-Catalytic Wittig Reaction”

Song Lin, Cornell University, $25,000
“Electrocatalytic Fluorination Reactions Using Sustainable Fluorine Sources”

Benjamin Wileyn & Jennifer Roizen, Duke University, $25,000
“C-H/C-H Cross-Coupling of Aromatic Compounds with Flow-Through Nanowire Electrode”

Jennifer L. Stockdill, Wayne State University, $50,000
“Catalytic Desulfurization of Peptides”

Corey Stephenson, University of Michigan, $50,000
“A Microfluidic Platform for Discovery and Optimization of Photoredox Reactions”

Jennifer L. Stockdill, Wayne State University, $50,000
“A Green Strategy for the Synthesis of Head-to-Tail Macrocyclic Peptides”

James Kiddle, Western Michigan University, $25,000
“The Wittig Reaction Metamorphosis from Phosphorus to Boron”

Stephen G. Newman, University of Ottawa, $25,000
“Using Flow Chemistry to Harness Ozone as a Sustainable Oxidant for C–H Functionalization”

Andrew Texeira, Worcester Polytechnic Institute, $25,000
“Enhanced Site-Accessibility for Solid-Phase Coupling in Hierarchical Materials”

Dennis Hall, University of Alberta, $25,000
“Borate-Based Catalytic Directing Groups for Alkene and C–H Functionalization Reactions Using Readily Available Alcohol Substrates”

Oana Luca, University of Colorado – Boulder, $25,000
“Catalyst and Electrolyte-Free Direct Electrochemical Cross Coupling”

Jeff Byers, Boston College, $25,000
“Development of an Iron-Based Catalyst for Suzuki-Miyaura Cross Coupling Reactions”

Zach Amara, National Des Arvts Et Métiers, $25,000
“Smart Synthesis with Magnetically Recoverable Visible Light Photocatalysts”

Leo Choe Peng, Universiti Sains Malaysia, $16,000
“Diafiltration of Monoclonal Antibody using pH Responsive Membrane with Positive Charge.

Andrew Zydney, Penn State, $50,000
“Countercurrent Staged Diafiltration for Monoclonal Antibody Formulation.”

Amanda Evans, California State University, Fullerton, $50,000
“Enz-Flow/Continuous Bioprocessing: Towards a green continuous flow synthesis of levomilnacipran”

A. John Blacker, University of Leeds, $50,000
“Process Development of Continuous Flow Oxidative Biotransformations”

Graham Dobereiner, Temple University, $50,000
“Tandem Catalytic Process in Flow: Synthesis of amides via mild photochemical carbonylation using CO2 as a carbonyl source”

Amanda C. Evans, California State University, $50,000
“Enz-Flow/Continuous Bioprocessing: Towards a green continuous flow synthesis of levomilnacipran”

Matthias Beller, Leibniz-Institut für Katalyse, $50,000
“Hydrogenation of Amides promoted by Ru- and Fe-Pincer Complexes—Ligand-Metal Cooperative Catalysis for the Mild and Selective Synthesis of Amines”

Neal Mankad, University of Illinois at Chicago, $100,000
“Bimetallic Approach to Iron-Catalyzed Coupling Reactions”

Paul Chirik, Princeton University, $100,000
“Modern Alchemy: New Paradigms for Enabling Base Metal-Catalyzed Cross-Coupling in the Pharmaceutical Industry”

Daniel Weix, University of Rochester, $50,000
“Direct Synthesis of Alkylated Arenes and Heteroarenes from the Cross-Coupling of Heteroaromatic Halides in Non-Amide Solvents”

Janet Scott, University of Bath, $100,000
“Intelligent Selection of Greener Solvents”

Neil Garg, UCLA, $60,000
“Development of Green Nickel-Catalyzed Cross-Coupling Reactions”

Shannon Stahl, University of Wisconsin-Madison, $150,000
“Oxidation/Epoxidation Methods Without the Use of Chlorinated Solvents: Chemoselective Aerobic Alcohol Oxidation Catalyzed by Earth-Abundant Metals”

Wei Zhang, University of Massachusetts-Boston, $25,000
“Greener Grignard Reactions”

Charles Liotta, Georgia Tech University, $150,000
“Green and Effective Continuous Catalytic Homo-Nazarov Cyclization Towards Multi-Step Synthesis of Heteroaromatic Ring-Fused Clyclohexanones”

David Cole-Hamilton, University of St. Andrews, $150,000
“Amide Hydrogenation to Amines”

Robert Crabtree, Yale University, $160,000
“Atom Economic Alcohol Activation and Amide Synthesis Using Base-Metal Catalysts Heterogenized on Titania Nanoparticles”

Chao-Jun Li, McGill University, $130,000
“Chiral Amines via Asymmetric Multi-component Reactions”

Michael Krische, University of Texas-Austin, $129,000
“Byproduct-Free Synthesis of Chiral Amines via C-C Bond Forming Transfer Hydrogenation and Hydrogen Auto-Transfer”

Robert Maleczka and Milton Smith, Michigan State University, $100,000
“Catalytic C-H Activation/Cross-Coupling of Aromatics (Avoiding the Preparation of Haloaromatics)”

Jianliang Xiao, University of Liverpool, $126,166
“Hydrogenation of Amides by Multifunctional Catalysts via Ground State Destabilisation”